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Name :
MAGEA4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAGEA4 Rabbit Polyclonal antibody. Positive WB detected in human placenta tissue, A375 cells. Positive IHC detected in human breast cancer tissue. Observed molecular weight by Western-blot: 35-40 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
Cancer/testis antigen 1.4 antibody; CT1.4 antibody; MAGE 4 antigen antibody; MAGE 41 antibody; MAGE 41 antigen antibody; MAGE X2 antibody; MAGE X2 antigen antibody; MAGE4 antibody; MAGE4A antibody; MAGE4B antibody; MAGEA4 antibody; melanoma antigen family A antibody; Melanoma assOCiated antigen 4 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_001011548). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
MAGEA4, also named as MAGE4 and CT1.4, is one of the germ cell-specific markers (PMID:16540528). SMAGEA4 is one of subgroup I MAGEAs members which may play important roles in the immune surveillance of certain tumor types and play important roles during embryogenesis.(PMID:15222021) The antibody is specific to MAGEA4.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel