Name :
MALT1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MALT1 Mouse Monoclonal antibody. Positive IF detected in HeLa cells. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 100 kDa
Tested applications :
ELISA, WB, IF
Species reactivity :
Human; other species not tested.
Alternative names :
DKFZp434L132 antibody; MALT1 antibody; MLT antibody; MLT1 antibody; Paracaspase antibody
Immunogen :
Human MALT1 Recombinant protein (His tag)
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of MALT1 recombinant protein (Accession Number: NM_173844). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IF: 1:50-1:500
Background :
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 belongs to caspase-like protein superfamily.MALT1 plays a potential role in the regulation of apoptosis and induces NFKB activation and required for the normal development of B cells and for the activation of the IKK complex.It acts as a caspase and mediates additional functions related to T cell activation, cleaving both the ubiquitin editing enzyme,TNFAIP3,and the C terminus of BCL10 .It has two isoforms.Researches showed that inhibition of MALT1 blocks A20 and BCL10 cleavage, reduces NFKB activity, and decreases the expression of NFKB targets BCLXL.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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