Name :
MAML3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MAML3 Rabbit Polyclonal antibody. Positive IF detected in HEK-293 cells. Positive WB detected in HEK-293 cells. Observed molecular weight by Western-blot: 122 kDa
Tested applications :
ELISA, WB, IF
Species reactivity :
Human; other species not tested.
Alternative names :
CAGH3 antibody; ERDA3 antibody; GDN antibody; KIAA1816 antibody; MAM 2 antibody; Mam 3 antibody; MAM2 antibody; MAML3 antibody; mastermind like 3 (Drosophila) antibody; Mastermind like protein 3 antibody; TNRC3 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MAML3 recombinant protein (Accession Number: NM_018717). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IF: 1:20-1:200
Background :
The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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