Name :
MAOA antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MAOA Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue, human kidney tissue, human liver tissue, human pancreas tissue. Positive IP detected in human placenta tissue. Positive WB detected in human placenta tissue. Observed molecular weight by Western-blot: 60 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human; other species not tested.
Alternative names :
MAO A antibody; MAOA antibody; monoamine oxidase A antibody; Monoamine oxidase type A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MAOA recombinant protein (Accession Number: NM_000240). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
MAOA belongs to the flavin monoamine oxidase family. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
References :
Saller S, Merz-Lange J, Raffael S. Norepinephrine, active norepinephrine transporter, and norepinephrine-metabolism are involved in the generation of reactive oxygen species in human ovarian granulosa cells. Endocrinology. 153(3):1472-83. 2012. Lee NC, Shieh YD, Chien YH. Regulation of the dopaminergic system in a murine model of aromatic L-amino acid decarboxylase deficiency. Neurobiology of disease. 52:177-90. 2013. Sai T, Uchida K, Nakayama H. Changes of MAO-A and MAO-B Expressions in the Placenta of MPTP or MPP(+) Treated Mice. Journal of toxicologic pathology. 26(1):73-7. 2013. Baandrup JD, Markvardsen LH, Peters CD. Pressure load: the main factor for altered gene expression in right ventricular hypertrophy in chronic hypoxic rats. PloS one. 6(1):e15859. 2011. Li J, Yang XM, Wang YH. Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling. Journal of hepatology. 60(6):1225-34. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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