Name :
MAP1B antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MAP1B Rabbit Polyclonal antibody. Positive WB detected in mouse cerebellum tissue, human brain tissue. Positive FC detected in SH-SY5Y cells. Positive IHC detected in mouse brain tissue. Positive IF detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 320kd
Tested applications :
ELISA, WB, IHC, FC, IF
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
MAP 1B antibody; MAP1B antibody; MAP5 antibody
Immunogen :
Human MAP1B Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MAP1B recombinant protein (Accession Number: BC141853). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100
Background :
Microtubule-associated protein 1B (MAP1B) is a cytoskeleton protein which can promote microtubule assembly. Previous reports have suggested that this protein is closely involved in neuronal development based on its extensive expression in the developing brain and moderate in mature neurons. Gene disruption or knockout studies of the MAP1B gene led to a delayed development of the nervous system in mice. It includes the N-terminal heavy chain and a C-terminal light chain. The MAP1B heavy chain has a microtubule-stabilization effect, and contains an actin-binding site that may play a role in the crosslinking of actin and microtubules, a function that may be important in neurite elongation. Various isoforms around 300-350 kDa of MAP1B can be observed due to the differences in phosphorylation state. (10704485)
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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