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Name :
MAP4K1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAP4K1 Rabbit Polyclonal antibody. Positive WB detected in Raji cells, Jurkat cells. Positive IP detected in Jurkat cells. Observed molecular weight by Western-blot: 90 kDa

Tested applications :
ELISA, WB, IP

Species reactivity :
Human; other species not tested.

Alternative names :
HPK1 antibody; MAP4K1 antibody; MEK kinase kinase 1 antibody; MEKKK 1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MAP4K1 recombinant protein (Accession Number: NM_007181). Purification method: Antigen Affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:500-1:5000

Background :
MAP4K1(Mitogen-activated protein kinase kinase kinase kinase 1) is also named as MEKKK 1, HPK1 and belongs to the protein kinase superfamily. It may function as a novel tumor suppressor and its loss plays a critical role in pancreatic cancer. MAP4K1 regulates stress responses, proliferation, and apoptosis in hematopoietic cells. This protein has 2 isoforms produced by alternative splicing.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel