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Name :
MAP4K3 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAP4K3 Rabbit Polyclonal antibody. Positive WB detected in human skeletal muscle tissue, HeLa cells, human brain tissue. Positive IHC detected in human skeletal muscle tissue, human heart tissue. Observed molecular weight by Western-blot: 100kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
GLK antibody; MAP4K3 antibody; MAPKKKK3 antibody; MEK kinase kinase 3 antibody; MEKKK 3 antibody; RAB8IPL1 antibody

Immunogen :
Human MAP4K3 Recombinant protein (His tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MAP4K3 recombinant protein (Accession Number: NM_001270425). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IHC: 1:20-1:200

Background :
MAP4K3(Mitogen-activated protein kinase kinase kinase kinase 3) has kinase activity and that it activates JNK but not MAPK1, MAPK3 or MAPK14 through the activation of MAP3K1 and MAP2K4. Endogenous MAP4K3 kinase activity could be stimulated by exposure to ultraviolet radiation or to tumor necrosis factor.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel