Share this post on:

Name :
MAPK11 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAPK11 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in human heart tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 42 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
MAP kinase 11 antibody; MAP kinase p38 beta antibody; MAPK 11 antibody; MAPK11 antibody; p38 2 antibody; P38B antibody; p38Beta antibody; P38BETA2 antibody; PRKM11 antibody; SAPK2 antibody; SAPK2B antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MAPK11 recombinant protein (Accession Number: NM_002751). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
MAPK11(Mitogen-activated protein kinase 11) is also named as PRKM11, SAPK2, SAPK2B,p38b and belongs to the MAP kinase subfamily.It is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors.In mouse brain, both p38a and p38b are present in neurons, while p38b is also expressed in glial cells(PMID:15748168).

References :
Zheng S, Yang C, Liu T. Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Phospho-Histone H2A.X(S139) Rabbit mAb In Vitro
Phospho-NFKB1(Ser337) Antibody web
LIAS Antibody: LIAS Antibody is an unconjugated, rabbit-derived, anti-LIAS polyclonal antibody. LIAS Antibody can be used for: ELISA, IHC-P, ICC, IF, expriments in mouse and predicted: human, rat, chicken, dog, pig, cow, horse, rabbit, sheep background without labeling.

Share this post on:

Author: Gardos- Channel