Name :
MAPK11 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MAPK11 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in human heart tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 42 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
MAP kinase 11 antibody; MAP kinase p38 beta antibody; MAPK 11 antibody; MAPK11 antibody; p38 2 antibody; P38B antibody; p38Beta antibody; P38BETA2 antibody; PRKM11 antibody; SAPK2 antibody; SAPK2B antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MAPK11 recombinant protein (Accession Number: NM_002751). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
MAPK11(Mitogen-activated protein kinase 11) is also named as PRKM11, SAPK2, SAPK2B,p38b and belongs to the MAP kinase subfamily.It is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors.In mouse brain, both p38a and p38b are present in neurons, while p38b is also expressed in glial cells(PMID:15748168).
References :
Zheng S, Yang C, Liu T. Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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