Name :
MAPKAPK5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MAPKAPK5 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, Jurkat cells. Positive IP detected in HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 54 kDa
Tested applications :
ELISA, WB, IP, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
MAPKAP kinase 5 antibody; MAPKAPK 5 antibody; MAPKAPK5 antibody; PRAK antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MAPKAPK5 recombinant protein (Accession Number: NM_003668). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IF: 1:50-1:500
Background :
MAPKAPK5(MAP kinase-activated protein kinase 5) is also named as PRAK and belongs to the CAMK Ser/Thr protein kinase family. MAPKAPK5 contains the conserved protein kinase domains I through XI, which are characteristic of all protein kinases. It is a major stress-activated kinase that can phosphorylate small heat shock protein, suggesting a potential role for PRAK in mediating stress-induced HSP27 phosphorylation in vivo(PMID:9628874). It has 2 isoforms produced by alternative splicing.
References :
Dwyer SF, Gelman IH. Cross-Phosphorylation and Interaction between Src/FAK and MAPKAP5/PRAK in Early Focal Adhesions Controls Cell Motility. Journal of cancer biology & research. 2(1):. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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