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Name :
MAPRE2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAPRE2 Rabbit Polyclonal antibody. Positive IF detected in mouse cells. Positive WB detected in K-562 cells, Jurkat cells. Observed molecular weight by Western-blot: 39-42 kDa

Tested applications :
ELISA, WB, IF

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
APC binding protein EB2 antibody; EB1 antibody; EB2 antibody; End binding protein 2 antibody; MAPRE2 antibody; RP1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MAPRE2 recombinant protein (Accession Number: NM_014268). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IF: 1:50-1:500

Background :
RP1 protein shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family and binds specifically to the C-terminal region of the APC protein. RP1 also binds directly to tubulin, both in vitro and in vivo. The function of RP1 is currently unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. It may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel