Name :
MARCH5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MARCH5 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Positive IP detected in HeLa cells. Positive IHC detected in human skeletal muscle tissue. Observed molecular weight by Western-blot: 31 kDa
Tested applications :
ELISA, IHC, IP, WB
Species reactivity :
Human; other species not tested.
Alternative names :
FLJ20445 antibody; MARCH V antibody; MARCH5 antibody; MitOChondrial ubiquitin ligase antibody; MITOL antibody; RING finger protein 153 antibody; RNF153 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MARCH5 recombinant protein (Accession Number: NM_017824). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:1000IHC: 1:20-1:200
Background :
MARCH5(E3 ubiquitin-protein ligase MARCH5) is a 31 kDa protein also named as RNF153. This protein plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway(PMID:19741096). And it may regulate MAP1B LC1 function in mitochondria by controlling mitochondrial aggregation via mitochondrial LC1 levels(PMID:22308378).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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