Name :
MARVELD2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MARVELD2 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, HEK-293 cells. Observed molecular weight by Western-blot: 64kd
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DFNB49 antibody; FLJ30532 antibody; MARVD2 antibody; MARVEL domain containing 2 antibody; MARVELD2 antibody; MRVLDC2 antibody; Tric antibody; Tricellulin antibody
Immunogen :
Human MARVELD2 Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MARVELD2 recombinant protein (Accession Number: XM_005248446). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
MARVELD2, also named as Tricellulin or TRIC, is a 558 amino acid protein, which contains one MARVEL domain. MARVELD2 localizes the cell membrane and plays a role in the formation of the epithelial barriers. MARVELD2, is a first integral membrane protein that is concentrated at the vertically oriented tight junction strands of tricellular contacts. MARVELD2 may be a component to maintain the integrity for peripheral nervous system myelin function and morphology.
References :
Nayak G, Lee SI, Yousaf R. Tricellulin deficiency affects tight junction architecture and cochlear hair cells. The Journal of clinical investigation. 123(9):4036-49. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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