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Name :
Anti-CALD1 Rabbit antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
CALD1 Rabbit polyclonal antibody

Tested applications :
WB, IHC-P, ICC/IF, FC, IP

Species reactivity :
Human, Mouse, Rat

Alternative names :
CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic peptide of human Caldesmon

Clonality :
Polyclonal

Formulation :
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage instructions :
Store at -20°C. Stable for 12 months from date of receipt.

Applications :
WB: 1/2000-1/10000IHC: 1/20ICC/IF: 1/50-1/200FC: 1/20IP: 1/20

Background :
Swiss-Prot Acc.Q05682.Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration .

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel