Name :
Anti-Caldesmon/CDM Rabbit antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Caldesmon/CDM Rabbit monoclonal antibody
Tested applications :
WB, IHC-P
Species reactivity :
Human
Alternative names :
Immunogen :
Isotype :
IgG
Preparation :
Antigen: A synthetic peptide of human Caldesmon/CDM
Clonality :
Monoclonal
Formulation :
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/1000IHC: 1/20
Background :
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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