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Name :
MAX antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MAX Rabbit Polyclonal antibody. Positive IF detected in PC-3 cells. Positive IP detected in HEK-293 cells. Positive WB detected in HEK-293 cells, A549 cells, PC-3 cells. Observed molecular weight by Western-blot: 22 kDa

Tested applications :
ELISA, WB, IF, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
bHLHd4 antibody; bHLHd5 antibody; bHLHd6 antibody; bHLHd7 antibody; bHLHd8 antibody; MAX antibody; MYC assOCiated factor X antibody; orf1 antibody; Protein max antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MAX recombinant protein (Accession Number: NM_145112). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IP: 1:200-1:1000IF: 1:10-1:100

Background :
Max, a member of MAX family, contains a basic helix-loop-helix (bHLH) domain, is a transcription regulator. MAX can form a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5′-CAC[GA]TG-3′. The MYC-MAX complex is a transcriptional activator, while the MAD-MAX complex is a repressor. MAX could dimerizated with another bHLH protein to form a heterodimer, such MYC or MAD. Thus bands recognized by this antibody much larger than predicted.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel