Name :
MBD2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MBD2 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, A431 cells, HEK-293 cells, human brain tissue, RAW264.7 cells. Observed molecular weight by Western-blot: 43-45 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human, Rat; other species not tested.
Alternative names :
Demethylase antibody; DKFZp586O0821 antibody; DMTase antibody; MBD2 antibody; NY CO 41 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_003927). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
MBD2, also named as DMTase, binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. MBD2 binds hemi-methylated DNA as well. It recruits histone deacetylases and DNA methyltransferases. MBD2 acts as transcriptional repressor and plays a role in gene silencing. (PMID:9774669) This antibody is specific to MBD2. It recognize isoform1 and isoform2 of MBD2.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Cleaved-PARP1 Rabbit mAb manufacturer
Hexokinase I (YP6080) Mouse mAb Protocol
Bax Antibody (YA591): Bax Antibody (YA591) is a non-conjugated and Rabbit origined monoclonal antibody about 21 kDa, targeting to Bax. It can be used for WB,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse, Rat.
