Name :
MBD5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MBD5 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, human skeletal muscle tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 160kd
Tested applications :
ELISA, WB
Species reactivity :
human, mouse, rat; other species not tested.
Alternative names :
MBD5 antibody; MRD1 antibody; KIAA1461 antibody; FLJ30517 antibody; FLJ11113 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MBD5 recombinant protein (Accession Number: BC014534). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
In vertebrates, cytosine methylation in DNA is one of the major epigenetic modifications, which regulates many cellular events, including developmental gene expression, X chromosome inactivation, genome defense, and genomic imprinting . DNA methylation exerts regulatory functions by recruiting specific binding proteins that contain a highly conserved methyl-CpG binding domain (MBD) [PMID:12610534,16403636]. Methyl-CpG binding domain protein 5 (MBD5) belongs to the MBD family proteins, which play central roles in transcriptional regulation and development. It is a candidate gene involved in human 2q23.1 microdeletion syndrome [PMID:23077600].
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Trastuzumab emtansine (solution) EGFR
Mepolizumab (anti-IL5) custom synthesis
p38 Antibody: p38 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to p38. It can be used for WB,IP assays with tag free, in the background of Human.
