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Name :
MBNL3 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MBNL3 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue. Positive IHC detected in human skeletal muscle tissue. Observed molecular weight by Western-blot: 38 kDa

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
CHCR antibody; Cys3His CCG1 required protein antibody; FLJ11316 antibody; MBLX antibody; MBLX39 antibody; MBNL3 antibody; MBXL antibody; Muscleblind like protein 3 antibody; Protein HCHCR antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MBNL3 recombinant protein (Accession Number: NM_001170704). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
MBNL3, also named as Muscleblind-like protein 3 or Cys3His CCG1-required protein, is a 354 amino acid protein, which contains four C3H1-type zinc fingers and belongs to the muscleblind family. MBNL3 localizes in the nucleus and is highly expressed in the placenta. MBNL3 mediates pre-mRNA alternative splicing regulation and plays a role in myotonic dystrophy pathophysiology. MBNL3 could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel