Name :
Anti-Calmodulin 2 / CALM2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Rabbit polyclonal to Calmodulin 2 / CALM2
Tested applications :
ELISA, WB
Species reactivity :
Human Calmodulin 2 / CALM2
Alternative names :
1500001E21Rik antibody; AL024017 antibody; CALM2 antibody; Calm2 antibody; calmodulin antibody; calmodulin antibody; calmodulin 2 antibody; calmodulin 2 (phosphorylase kinase antibody; caM antibody; caM antibody; CAMII antibody; delta) antibody; LP7057 protein antibody; PHKD antibody; PHKD2 antibody; phosphorylase kinase delta antibody; caM antibody; PHKD antibody; CAMII antibody; LQT15 antibody; PHKD2 antibody; AL024017 antibody; 1500001E21Rik antibody
Immunogen :
Human Calmodulin 2 / CALM2 (His Tag) recombinant protein
Isotype :
Rabbit IgG
Preparation :
Produced in rabbits immunized with purified, recombinant Human Calmodulin 2 / CALM2 (rh Calmodulin 2 / CALM2; P62158; Met1-Lys149). Calmodulin 2 / CALM2 specific IgG was purified by Human Calmodulin 2 / CALM2 affinity chromatography.
Clonality :
Polyclonal
Formulation :
0.2 μm filtered solution in PBS with 5% trehalose
Storage instructions :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Applications :
WB: 10-30 μg/mlELISA: 0.1-0.2 μg/mLThis antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human Calmodulin 2 / CALM2. The detection limit for Human Calmodulin 2 / CALM2 is
Background :
Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most abundantly expressed in articular chondrocytes and OA cartilage.
References :
Egli R, et al. (1993) Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3. Genomics. 16(2): 461-5. Mikiko, et al. (2002) Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. Mol Biol Cell. 13(9):3235-45. SenGupta B, et al. (1987) Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species. J Biol Chem. 262(34): 16663-70.
Related websites: https://www.medchemexpress.com/antibodies.html
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