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Name :
MCM7 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MCM7 Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells, A431 cells, HeLa cells, MCF7 cells. Positive IP detected in NIH/3T3 cells. Positive IF detected in NIH/3T3 cells. Positive IHC detected in human lung cancer tissue, human lymphoma tissue. Positive FC detected in Raji cells. Observed molecular weight by Western-blot: 81 kDa

Tested applications :
ELISA, WB, IP, IHC, IF, FC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
CDABP0042 antibody; CDC47 antibody; CDC47 homolog antibody; MCM2 antibody; MCM7 antibody; P1.1 MCM3 antibody; P1CDC47 antibody; P85MCM antibody; PNAS 146 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MCM7 recombinant protein (Accession Number: NM_005916). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:1000-1:10000IHC: 1:20-1:200IF: 1:50-1:500

Background :
Genes encoding PPR (pentatricopeptide repeat)-containing proteins constitute one of the largest gene families in plants. The majority of these proteins are predicted to target organelles and to bind to RNA. Strikingly, there is a dearth of these proteins in mammals, although genomic searches reveal six candidates, all of which are also predicted to target the mitochondrion. One of these proteins, MRPS27is participated in transcription and translation respectively. [PMID:18939947] MRPS27is a component of the small subunit of the mitochondrial ribosome that is encoded by the nuclear genome [PMID: 11279123].

References :
Du R, Long J, Yao J. Subcellular quantitative proteomics reveals multiple pathway cross-talk that coordinates specific signaling and transcriptional regulation for the early host response to LPS. Journal of proteome research. 9(4):1805-21. 2010.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel