Name :
MED10 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MED10 Rabbit Polyclonal antibody. Positive WB detected in COLO 320 cells. Observed molecular weight by Western-blot: 16 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
MED10 antibody; mediator complex subunit 10 antibody; NUT2 antibody; TRG 17 antibody; TRG 20 antibody; TRG17 antibody; TRG20 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MED10 recombinant protein (Accession Number: NM_032286). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000
Background :
MED10, also named as L6, TRG17, or TRG20, is a 135 amino acid protein, which belongs to the Mediator complex subunit 10 family. MED10 localizes in the nucleus and as a component of the Mediator complex, a coactivator is involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Multiprotein mediator complex acting as a coactivator is required for activation of RNA polymerase II transcription by DNA bound transcription factors.
References :
Vijayalingam S, Chinnadurai G. Adenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complex. Journal of virology. 87(6):3425-34. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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