Name :
Acetylcholinesterase antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Acetylcholinesterase Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, NIH/3T3 cells. Positive IHC detected in human liver tissue. Observed molecular weight by Western-blot: 66-72 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Acetylcholinesterase antibody; ACHE antibody; ARACHE antibody; N ACHE antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Acetylcholinesterase recombinant protein (Accession Number: BC094752). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
The classical role of acetylcholinesterase (AChE) is to terminate cholinergic neurotransmission by rapid hydrolysis of the neurotransmitter acetylcholine (ACh) at cholinergic synapses and neuromuscular junctions(PMID:20054652). AChE activity is significantly lower in aspirates from squamous cell carcinomas and the molecular distribution of AChE in both bronchial cells and fluids consisted of amphiphilic monomers and dimers(PMID:18211261). It has 4 isoforms produced by alternative splicing.
References :
Wu YY, Wang X, Tan L. Lithium attenuates scopolamine-induced memory deficits with inhibition of GSK-3β and preservation of postsynaptic components. Journal of Alzheimer’s disease : JAD. 37(3):515-27. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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