Name :
MED8 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MED8 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, mouse liver tissue, SGC-7901 cells. Observed molecular weight by Western-blot: 29 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
ARC32 antibody; MED8 antibody; mediator complex subunit 8 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MED8 recombinant protein (Accession Number: BC010543). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
MED8, a component of the Mediator complex, is a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. It plays a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins. MED8 has three isoforms with MW 19 kDa, 29 kDa and 33 kDa. And the ubiquitination form will be 38-43 kDa.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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