Share this post on:

Name :
MEIS2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MEIS2 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, PC-3 cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 56kd

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Homeobox protein Meis2 antibody; HsT18361 antibody; Meis homeobox 2 antibody; Meis1 related protein 1 antibody; MEIS2 antibody; MRG1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MEIS2 recombinant protein (Accession Number: NM_002399). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
MEIS2, also named as Meis1-related protein 1 or MRG1, is a 477 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the TALE/MEIS homeobox family. MEIS2 is expressed in various tissues and at high level in the lymphoid organs of hematopoietic tissues. MEIS2 localizes in the nucleus and is involved in transcriptional regulation. MEIS2 is a critical downstream effector within an essential homeoprotein network that serving a rate-limiting regulatory role in MLL leukemogenesis. MEIS2 as midbrain specific marker is upregulated concomitantly with the morphological transformation of hindbrain to midbrain.

References :
Russell MK, Longoni M, Wells J. Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes. Proceedings of the National Academy of Sciences of the United States of America. 109(8):2978-83. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Ixekizumab Epigenetic Reader Domain
Risankizumab Purity & Documentation
C5b-9 Antibody: C5b-9 Antibody is an unconjugated, rabbit-derived, anti-C5b-9 polyclonal antibody. C5b-9 Antibody can be used for: WB, IHC-P, IHC-F, IF expriments in human, rat, and predicted: mouse background without labeling.

Share this post on:

Author: Gardos- Channel