Name :
MEK1-Specific antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MEK1-Specific Rabbit Polyclonal antibody. Positive IHC detected in human endometrial cancer tissue, human colon tissue.
Tested applications :
ELISA, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
ERK activator kinase 1 antibody; MAP kinase kinase 1 antibody; MAP2K1 antibody; MAPK/ERK kinase 1 antibody; MAPKK 1 antibody; MAPKK1 antibody; MEK 1 antibody; MEK1 antibody; MKK1 antibody; PRKMK1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_002755). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IHC: 1:20-1:200
Background :
MEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling(PMID:19219045). It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated(PMID:21144847). This antibody is specific to MEK1.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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