Name :
MEPCE antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MEPCE Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells. Positive WB detected in MCF7 cells. Positive IP detected in MCF-7 cells. Observed molecular weight by Western-blot: 74 kDa
Tested applications :
ELISA, WB, IF, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Bin3 homolog antibody; FLJ20257 antibody; MEPCE antibody; methylphosphate capping enzyme antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MEPCE recombinant protein (Accession Number: NM_019606). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:1000IF: 1:20-1:200
Background :
MEPCE is a somponent of the 7SK snRNP complex, and a S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5′-end of 7SK snRNA, which leads to its stabilization.
References :
Mizutani T, Ishizaka A, Suzuki Y, Iba H. 7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts. FEBS letters. 588(9):1630-6. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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