Name :
MEPE antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MEPE Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, A2780 cells, HeLa cells. Observed molecular weight by Western-blot: 43kd,98kd
Tested applications :
ELISA, WB
Species reactivity :
human; other species not tested.
Alternative names :
MEPE antibody; Osteoblast/osteOCyte factor 45 antibody; OF45 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_020203). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000
Background :
Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is amember of the small integrin-binding ligand N-linked glycopro-tein (SIBLING) family (PMID: 12952171). MEPE promotes renal phosphate excretion and modulates mineralization (PMID: 22582013). It can be phosphorylated by secreted protein kinases. (PMID: 14962809). MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines (PMID: 14962809; 20145617). It is a 525-amino acid protein with a calculated molecular weight of 58 kDa. This antibody raised against a synthetic peptide (CTHGRKYHYVPHRQNNSTR) detects a major band (43 kDa) and two minor bands (98 kDa and 34 kDa).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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