Name :
Anti-CaMKII alpha Rabbit antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
CaMKII alpha Rabbit polyclonal antibody
Tested applications :
WB, ICC/IF, FC
Species reactivity :
Human, Mouse, Rat
Alternative names :
CAMKA; MRD53; MRT63; CaMKIINalpha antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide of human CaMKII
Clonality :
Polyclonal
Formulation :
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage instructions :
Store at -20°C. Stable for 12 months from date of receipt.
Applications :
WB: 1/1000-1/2000ICC/IF: 1/20-1/100FC: 1/20-1/100
Background :
Swiss-Prot Acc.Q9UQM7.Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission . Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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