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Name :
MFAP4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MFAP4 Rabbit Polyclonal antibody. Positive IHC detected in human ovary tissue, human lung tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue. Positive WB detected in human kidney tissue, mouse heart tissue, mouse lung tissue, rat lung tissue. Observed molecular weight by Western-blot: 36kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
MFAP4 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MFAP4 recombinant protein (Accession Number: NM_002404). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
Microfibrillar-associated protein 4 (MFAP4) is a extracellular matrix glycoprotein containing a fibrinogen C-terminal domain and a N-terminal located integrin-binding motif. It could be involved in calcium-dependent cell adhesion or intercellular interactions. MFAP4 gene is commonly deleted in Smith-Magenis syndrome patients. (PMID: 7633408; 16867155; 10542261; 18322703)

References :
Muraoka S, Kume H, Watanabe S. Strategy for SRM-based verification of biomarker candidates discovered by iTRAQ method in limited breast cancer tissue samples. Journal of proteome research. 11(8):4201-10. 2012. Brandsma CA, van den Berge M, Postma DS. A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD. Thorax. 70(1):21-32. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel