Name :
MGAT4C antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MGAT4C Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells, mouse testis tissue. Positive IP detected in mouse testis tissue. Observed molecular weight by Western-blot: 55 kDa
Tested applications :
ELISA, WB, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
GlcNAc T IVc antibody; GnT IVc antibody; GNTIVH antibody; HGNT IV H antibody; MGAT4C antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MGAT4C recombinant protein (Accession Number: XM_017019150). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:1000
Background :
MGAT4C is predicted to be a glycosyltransferase that catalyzes a GlcNAc β1-4 linkage to the core mannose residues of N-glycans, resulting in N-glycans with tri- or tetraantennary structures.Recently MGAT4C has been found to get involved in processing complex N-glycan structures on CD133 and CD133 has been identified as a substrate of MGAT4C. Given to the fact that CD133 is widely used as a marker of numerous stem cell and cancer stem cell types, MGAT4C may have an important role in certain cancers.(21937449)
References :
Mak AB, Blakely KM, Williams RA. CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope. The Journal of biological chemistry. 286(47):41046-56. 2011.
Related websites: https://www.medchemexpress.com/antibodies.html
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