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Name :
MGLL antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MGLL Rabbit Polyclonal antibody. Positive IP detected in mouse liver tissue. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human liver cancer tissue.

Tested applications :
ELISA, IHC, WB, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
HU K5 antibody; HUK5 antibody; Lysophospholipase homolog antibody; Lysophospholipase like antibody; MGL antibody; MGLL antibody; Monoglyceride lipase antibody

Immunogen :
Human MGLL Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MGLL recombinant protein (Accession Number: NM_007283). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:1000IHC: 1:20-1:200

Background :
MGLL(monoglyceride lipase) is also named as MAGL, HU-K5 and belongs to the monoacylglycerol lipase family. It converts monoacylglycerides to free fatty acids and glycerol and functions together with hormone-sensitive lipase (HSL) in the mobilization of fatty acids from the triglyceride stores of adipocytes. MGL prootein is ubiquitously expressed in kidney, spleen, heart, liver, stomach, brain, lung, adrenal gland, adipose tissue and in brain,there are two bands of 33 kDa and 35 kDa can be detected. The single protein species expressed in muscle is larger(around 40 kDa).(PMID:11470505). This protein can exsit as a homodimer(PMID:19957260).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel