Name :
mGluR1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
mGluR1 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, mouse brain tissue. Positive IHC detected in mouse brain tissue. Observed molecular weight by Western-blot: 54 kDa,102 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
GPRC1A antibody; GRM1 antibody; GRM1A antibody; mGlu1 antibody; mGluR1 antibody; MGLUR1A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_000838). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:50-1:500
Background :
GRM1, also named as GPRC1A and MGLUR1, belongs to the G-protein coupled receptor 3 family. GRM1 is a receptor for glutamate. The activity of GRM1 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. It may participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. The antibody can recognize isoform1 and isoform2 of GRM1.
References :
Koochekpour S, Majumdar S, Azabdaftari G. Serum glutamate levels correlate with Gleason score and glutamate blockade decreases proliferation, migration, and invasion and induces apoptosis in prostate cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research. 18(21):5888-901. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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