Name :
MGME1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MGME1 Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human liver cancer tissue. Positive WB detected in Jurkat cells, A549 cells, HEK-293 cells, HepG2 cells, mouse liver tissue, Y79 cells. Observed molecular weight by Western-blot: 36-39 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
bA504H3.4 antibody; C20orf72 antibody; DDK1 antibody; FLJ14597 antibody; MGME1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MGME1 recombinant protein (Accession Number: XM_017028127). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
MGME1, also named as C20orf72, is a single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. It has preference for 5′-3′ exonuclease activity. MGME1 cleaves single-stranded DNA (ssDNA) and several DNA or DNA-RNA chimeric oligonucleotides that showed free nucleic acid ends. It probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. This antibody detects the 35-40 kDa protein.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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