Name :
MICAL2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MICAL2 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive IF detected in HepG2 cells. Positive IP detected in PC-3 cells. Positive WB detected in PC-3 cells. Observed molecular weight by Western-blot: 95, 112 kDa
Tested applications :
ELISA, IHC, IF, WB, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DKFZp686H03148 antibody; DKFZp686H2469 antibody; KIAA0750 antibody; MICAL2 antibody; MICAL2PV1 antibody; MICAL2PV2 antibody; Protein MICAL 2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MICAL2 recombinant protein (Accession Number: XM_017018589). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IP: 1:200-1:1000IHC: 1:20-1:200IF: 1:10-1:100
Background :
MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions.There are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2. MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain and a Lin11, Isl-1 and Mec-3 (LIM) domain. It has been demonstrated that MICAL2 could regulate actin stress fibers and is required for normal actin organization. In addition, MICAL2-PV, a novel splicing variants of MICAL2, has been reported to be involved in cancer progression of prostate cancer. This antibody can recognize both MICAL2 and MICAL2-PV. This antibody recognizes various isoforms of MICAL2 around 90-95 kDa or 109-112 kDa.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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