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Name :
MKP-2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MKP-2 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in mouse brain tissue, A549 cells, HepG2 cells, mouse skin tissue, RAW264.7 cells, SMMC-7721 cells. Observed molecular weight by Western-blot: 50kd

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
dual specificity phosphatase 4 antibody; DUSP4 antibody; HVH2 antibody; MAP kinase phosphatase 2 antibody; MKP 2 antibody; MKP2 antibody; TYP antibody; VH2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MKP-2 recombinant protein (Accession Number: NM_001394). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
DUSP4, also named as MKP-2, is a member of the mitogen-activated protein (MAP) kinase phosphatase family which has been suggested to play an important role in the feedback control of MAP kinase-mediated gene expression. DUSP4 preferentially inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel