Name :
Anti-Carbonic Anhydrase 9/CA9 (5B5) Mouse antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Carbonic Anhydrase 9/CA9 (5B5) Mouse monoclonal antibody
Tested applications :
WB, IHC-P, FC
Species reactivity :
Human
Alternative names :
Immunogen :
Isotype :
Mouse IgG1
Preparation :
Antigen: Purified recombinant fragment of human CA9 expressed in E. Coli.
Clonality :
Monoclonal
Formulation :
Ascitic fluid containing 0.03% sodium azide.
Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/500 – 1/2000IHC: 1/200 – 1/1000FC: 1/200 – 1/400ELISA: 1/10000
Background :
Swiss-Prot Acc.Q16790.CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. Tissue specificity: Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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