Name :
MMAB antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MMAB Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human ovary tumor tissue. Positive IP detected in HeLa cells. Positive WB detected in HeLa cells, BxPC-3 cells, HepG2 cells, L02 cells. Observed molecular weight by Western-blot: 27 kDa
Tested applications :
ELISA, WB, IHC, IP, IF
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
ATR antibody; cblB antibody; MMAB antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MMAB recombinant protein (Accession Number: NM_052845). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:50-1:500
Background :
The MMAB gene encodes cob(I)alamin adenosyltransferase, which catalyzes the final step in the synthesis of the coenzyme adenosylcobalamin (Adocbl). Adocbl is a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. The deduced 250-amino acid protein has a calculated molecular mass of 27.3 kD.
References :
Jorge-Finnigan A, Aguado C, Sánchez-Alcudia R. Functional and structural analysis of five mutations identified in methylmalonic aciduria cblB type. Human mutation. 31(9):1033-42. 2010. Jorge-Finnigan A, Brasil S, Underhaug J. Pharmacological chaperones as a potential therapeutic option in methylmalonic aciduria cblB type. Human molecular genetics. 22(18):3680-9. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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