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Name :
MMP20 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MMP20 Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human liver cancer tissue. Positive WB detected in mouse brain tissue, rat brain tissue. Observed molecular weight by Western-blot: 54 kDa

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Enamel metalloproteinase antibody; Enamelysin antibody; matrix metallopeptidase 20 antibody; Matrix metalloproteinase 20 antibody; MMP 20 antibody; MMP20 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_004771). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100

Background :
MMP20 belongs to the peptidase M10A family. It degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). MMP20 may play a central role in tooth enamel formation. Defects in MMP20 are the cause of amelogenesis imperfecta hypomaturation type 2A2 (AI2A2). This antibody is specific to MMP20.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel