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Name :
MMP26 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MMP26 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive IF detected in SKOV-3 cells. Positive WB detected in SKOV-3 cells, HEK-293 cells, human placenta tissue. Observed molecular weight by Western-blot: 20 kDa

Tested applications :
ELISA, WB, IHC, IF

Species reactivity :
Human; other species not tested.

Alternative names :
Endometase antibody; Matrilysin 2 antibody; matrix metallopeptidase 26 antibody; Matrix metalloproteinase 26 antibody; MMP 26 antibody; MMP26 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MMP26 recombinant protein (Accession Number: NM_021801). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200

Background :
MMP26(matrix metallopeptidase 26) may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor.MMP26 is expressed in placenta and uterus and is widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines(PMID: 10987280).The proenzyme without the signal peptide has a calculated molecular mass of 29 KDa and the processed enzyme has a calculated molecular mass of 19KDa(PMID:15574774).This antibody is specific to MMP29.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel