Name :
MMP28 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MMP28 Rabbit Polyclonal antibody. Positive IF detected in A549 cells. Positive IHC detected in human kidney tissue, human ovary tissue, human skin cancer tissue, human testis tissue. Positive WB detected in A549 cells, human colon tissue, mouse heart tissue. Observed molecular weight by Western-blot: 48 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
EPILYSIN antibody; matrix metallopeptidase 28 antibody; Matrix metalloproteinase 28 antibody; MM28 antibody; MMP 28 antibody; MMP28 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MMP28 recombinant protein (Accession Number: NM_032950). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100
Background :
MMP28(Epilysin)can degrade casein and play a role in tissues homeostasis and repair .The only specific human cell type recognized to express epilysin is the basal keratinocyte in the skin, where epilysin expression is upregulated during wound repair(PMID:16940349).Western blot showed this antibody recognize bands at 62 and 58 kDa as well as breakdown products at 50, 48, and 46 kDa(PMID:15953044).This antibody is specific to MMP28.
References :
Zhang M, Liu Y, Feng H. CD133 affects the invasive ability of HCT116 cells by regulating TIMP-2. The American journal of pathology. 182(2):565-76. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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