Name :
acid phosphatase, prostate antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
acid phosphatase, prostate Rabbit Polyclonal antibody. Positive IF detected in PC-3 cells. Positive IHC detected in human prostate cancer tissue, human prostate hyperplasia tissue. Positive WB detected in PC-3 cells, COLO 320 cells, MCF7 cells, mouse lung tissue, mouse testis tissue. Observed molecular weight by Western-blot: 50-60 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
acid phosphatase antibody; prostate antibody; ACP 3 antibody; ACP3 antibody; ACPP antibody; PAP antibody; Prostatic acid phosphatase antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of acid phosphatase, prostate recombinant protein (Accession Number: NM_001134194). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200
Background :
ACPP is also named as PAP(prostatic acid phosphatase),5′-nucleotidase,thiamine monophosphatas and Belongs to the histidine acid phosphatase family.This enzyme is a homodimeric glycoprotein with a subunit molecular mass of 50 kDa and is an androgen-stimulated secretory product of the human prostate gland(PMID:8132635).It is also a non-specific phosphatase and has been implicated in the progression of prostate cancer, which inactivates LPA in human seminal plasma(PMID:15280042). This protein has three glycosylation sites(PMID:10639192;12525165).
References :
Bae H, Lim W, Bae SM, Bazer FW, Choi Y, Song G. Avian prostatic acid phosphatase: estrogen regulation in the oviduct and epithelial cell-derived ovarian carcinomas. Biology of reproduction. 91(1):3. 2014. Lim W, Bae H, Sohn JY, Jeong W, Kim SH, Song G. Dietary cholesterol affects expression of prostatic acid phosphatase in reproductive organs of male rats. Biochemical and biophysical research communications. 456(1):421-7. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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