Name :
MOCOS antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MOCOS Rabbit Polyclonal antibody. Positive IP detected in HepG2 cells. Positive WB detected in HepG2 cells. Positive IF detected in HepG2 cells. Positive IHC detected in human liver tissue. Observed molecular weight by Western-blot: 98 kDa
Tested applications :
ELISA, WB, IHC, IF, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
FLJ20733 antibody; HMCS antibody; MCS antibody; MOCo sulfurase antibody; MOCOS antibody; molybdenum cofactor sulfurase antibody; MOS antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of M℃OS recombinant protein (Accession Number: NM_017947). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:1000IHC: 1:20-1:200IF: 1:20-1:200
Background :
MocOS(Molybdenum cofactor sulfurase) is also named as MCS, MOS, hMCS and belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. It catalyzes the removal of elemental sulfur from cysteine to produce alanine. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. Defects in MocOS are the cause of xanthinuria type 2 (XU2)(PMID:17368066).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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