Product Name :
Bosentan
Description:
Bosentan is a mixed Endothelin Receptor Antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR. It is used for the treatment of pulmonary artery hypertension (PAH). Bosentan blocks the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
CAS:
147536-97-8
Molecular Weight:
551.61
Formula:
C27H29N5O6S
Chemical Name:
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2′-bipyrimidin]-4-yl]benzene-1-sulfonamide
Smiles :
COC1=CC=CC=C1OC1C(NS(=O)(=O)C2=CC=C(C=C2)C(C)(C)C)=NC(=NC=1OCCO)C1=NC=CC=N1
InChiKey:
GJPICJJJRGTNOD-UHFFFAOYSA-N
InChi :
InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bosentan is a mixed Endothelin Receptor Antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR. It is used for the treatment of pulmonary artery hypertension (PAH). Bosentan blocks the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.|Product information|CAS Number: 147536-97-8|Molecular Weight: 551.61|Formula: C27H29N5O6S|Chemical Name: 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2′-bipyrimidin]-4-yl]benzene-1-sulfonamide|Smiles: COC1=CC=CC=C1OC1C(NS(=O)(=O)C2=CC=C(C=C2)C(C)(C)C)=NC(=NC=1OCCO)C1=NC=CC=N1|InChiKey: GJPICJJJRGTNOD-UHFFFAOYSA-N|InChi: InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Formaldehyde dehydrogenase supplier |Shelf Life: ≥360 days if stored properly.Eribulin References |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32880190 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
