Product Name :
Lp-PLA2-IN-1
Description:
Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer’s disease research.
CAS:
1420367-28-7
Molecular Weight:
468.38
Formula:
C21H17F5N4O3
Chemical Name:
8-[(3,5-difluoro-4-[6-(trifluoromethyl)pyridin-3-yl]oxyphenyl)methoxy]-1-methyl-1H,2H,3H,4H,6H-[1,3]diazino[1,6-a]pyrimidin-6-one
Smiles :
CN1CCCN2C(=O)N=C(C=C21)OCC1C=C(F)C(OC2C=NC(=CC=2)C(F)(F)F)=C(F)C=1
InChiKey:
QJIGPJZJKXZSNF-UHFFFAOYSA-N
InChi :
InChI=1S/C21H17F5N4O3/c1-29-5-2-6-30-18(29)9-17(28-20(30)31)32-11-12-7-14(22)19(15(23)8-12)33-13-3-4-16(27-10-13)21(24,25)26/h3-4,7-10H,2,5-6,11H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Lp-PLA2-IN-1 is a potent Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-1 has the potential for atherosclerosis, Alzheimer’s disease research.Idelalisib Autophagy |Product information|CAS Number: 1420367-28-7|Molecular Weight: 468.N-Boc-piperazine TGF-beta/Smad 38|Formula: C21H17F5N4O3|Chemical Name: 8-[(3,5-difluoro-4-[6-(trifluoromethyl)pyridin-3-yl]oxyphenyl)methoxy]-1-methyl-1H,2H,3H,4H,6H-[1,3]diazino[1,6-a]pyrimidin-6-one|Smiles: CN1CCCN2C(=O)N=C(C=C21)OCC1C=C(F)C(OC2C=NC(=CC=2)C(F)(F)F)=C(F)C=1|InChiKey: QJIGPJZJKXZSNF-UHFFFAOYSA-N|InChi: InChI=1S/C21H17F5N4O3/c1-29-5-2-6-30-18(29)9-17(28-20(30)31)32-11-12-7-14(22)19(15(23)8-12)33-13-3-4-16(27-10-13)21(24,25)26/h3-4,7-10H,2,5-6,11H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33317373 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2 travels with low-density lipoprotein (LDL) and rapidly cleaves oxidized phosphatidylcholine molecules derived from the oxidation of LDL|Products are for research use only. Not for human use.|
