Name :
Anti-B3GAT3 / GLCATI antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Rabbit polyclonal to B3GAT3 / GLCATI
Tested applications :
ELISA, IHC-P
Species reactivity :
Human B3GAT3 / GLCATI
Alternative names :
GLCATI antibody; glcUAT-I antibody; 2810405M13Rik antibody; beta-1 antibody; 3-glucuronyltransferase 3 (glucuronosyltransferase I) antibody; B3GAT3 antibody; GLCATI antibody; Sqv-8-like protein antibody; UDP-GlcUA:Gal beta-1 antibody; 3-Gal-R glucuronyltransferase antibody; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 antibody; glcUAT-I antibody; beta-1 antibody; 3-glucuronyltransferase 3 (glucuronosyltransferase I) antibody; B3gat3 antibody; 2810405M13Rik antibody; UDP-GlcUA:Gal beta-1 antibody; 3-Gal-R glucuronyltransferase antibody; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 antibody; glcAT-I antibody; glcUAT-I antibody; glucuronosyltransferase I antibody; glucuronyltransferase I antibody
Immunogen :
Human B3GAT3 / GLCATI (His Tag) recombinant protein
Isotype :
Rabbit IgG
Preparation :
Produced in rabbits immunized with purified, recombinant Human B3GAT3 / GLCATI (rh B3GAT3 / GLCATI; NP_036332.2; Glu72-Val335). B3GAT3 / GLCATI specific IgG was purified by Human B3GAT3 / GLCATI affinity chromatography.
Clonality :
Polyclonal
Formulation :
0.2 μm filtered solution in PBS
Storage instructions :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Applications :
ELISA: 0.1-0.2 μg/mlThis antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Human B3GAT3 / GLCATI.IHC-P: 0.1-2 μg/mL
Background :
Glycosaminoglycans biosynthesis (PubMed:25893793). Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation (PubMed:24425863).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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