Name :
GNG2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GNG2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, mouse brain tissue. Observed molecular weight by Western-blot: 8 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
G gamma I antibody; GNG2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GNG2 recombinant protein (Accession Number: XM_017021377). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
Gγ2 subunit (Gng2/GNG2) is one of subunits of the Gβγ-dimer composing heterotrimeric G protein with a Gα-subunit. Heterotrimeric G protein has been reported to be involved in various biological activities including cell proliferation, differentiation, invasion and angiogenesis. It is expressed in a range of foetal tissues as well as adult testis, adrenal gland, brain, white blood cells and lung.
References :
Yajima I, Kumasaka MY, Yamanoshita O. GNG2 inhibits invasion of human malignant melanoma cells with decreased FAK activity. American journal of cancer research. 4(2):182-8. 2014. Yajima I, Kumasaka MY, Naito Y. Reduced GNG2 expression levels in mouse malignant melanomas and human melanoma cell lines. American journal of cancer research. 2(3):322-9. 2012. Yajima I, Kumasaka MY, Tamura H, Ohgami N, Kato M. Functional analysis of GNG2 in human malignant melanoma cells. Journal of dermatological science. 68(3):172-8. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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