Name :
GPAA1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GPAA1 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, mouse brain tissue. Observed molecular weight by Western-blot: 60-68 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
GAA1 antibody; GAA1 protein homolog antibody; GPAA1 antibody; hGAA1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GPAA1 recombinant protein (Accession Number: NM_003801). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000
Background :
GPAA1(Glycosylphosphatidylinositol anchor attachment 1 protein) is also named as GAA1. It is the most conspicuously hydrophobic of the known subunits of GPIT, and it may play a key role in substrate recognition. It is predicted to be a multispanning membrane protein of 67 kDa with seven transmembrane (TM) domains, a large lumenal domain between the first two TM segments, and a cytoplasmically oriented N terminus bearing a potential ER retrieval signal in the form of a diarginine motif(PMID:12052837). It has 2 isoforms produced by alternative splicing and the full length protein has 2 glycosylation sites. This antibody is specific to GPAA1.
References :
Nagpal JK, Dasgupta S, Jadallah S. Profiling the expression pattern of GPI transamidase complex subunits in human cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 21(8):979-91. 2008.
Related websites: https://www.medchemexpress.com/antibodies.html
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