Name :
Anti-BACE1 Rabbit antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
BACE1 Rabbit monoclonal antibody
Tested applications :
WB, IP
Species reactivity :
Mouse, Rat
Alternative names :
ASP2; Bace; C76936 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant protein of mouse BACE1
Clonality :
Monoclonal
Formulation :
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage instructions :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/1000IP: 1/20
Background :
Swiss-Prot Acc.P56818.Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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