Name :
GPD2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GPD2 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue, mouse liver tissue, mouse pancreas tissue. Positive IP detected in mouse skeletal muscle tissue. Positive IHC detected in human testis tissue, human brain tissue, human spleen tissue. Observed molecular weight by Western-blot: 68 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
GDH2 antibody; GPD M antibody; GPD2 antibody; GPDH M antibody; GPDM antibody; mGPDH antibody; mtGPD antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GPD2 recombinant protein (Accession Number: BC019874). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:500-1:5000IHC: 1:20-1:200
Background :
GPD2(Glycerol-3-phosphate dehydrogenase, mitochondrial) belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.It is phosphorylated only in capacitated hamster spermatozoa and is noncanonically localized in the acrosome and principal piece in human, mouse, rat, and hamster spermatozoa, though in somatic cells it is localized in the mitochondria. This noncanonical localization may imply a role of GPD2 in acrosome reaction and hyperactivation(PMID:19333995 ).
References :
Joshi M, Eagan J, Desai NK. A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia. European journal of human genetics : EJHG. 22(10):1229-32. 2014. Orr AL, Quinlan CL, Perevoshchikova IV, Brand MD. A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase. The Journal of biological chemistry. 287(51):42921-35. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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