Name :
GRB2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GRB2 Rabbit Polyclonal antibody. Positive IF detected in HEK-293 cells. Positive WB detected in HEK-293 cells, A431 cells, C2C12 cells, rat brain tissue, rat spleen tissue. Observed molecular weight by Western-blot: 25-28kd
Tested applications :
ELISA, WB, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Adapter protein GRB2 antibody; ASH antibody; EGFRBP GRB2 antibody; GRB2 antibody; Grb3 3 antibody; MST084 antibody; MSTP084 antibody; Protein Ash antibody; SH2/SH3 adapter GRB2 antibody
Immunogen :
Human GRB2 Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GRB2 recombinant protein (Accession Number: NM_002086). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IF: 1:10-1:100
Background :
GRB2 (growth factor receptor-bound protein 2) binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. N-SH3 domain of Grb2 was involved in the protein vesicular localization including amyloid-β protein precursor (AβPP). Involvement of GRB2 in Ras-signaling pathway has been reported, recent finding show that GRB2 may also play a complex role in T and B-cell antigen receptor signaling.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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